Hubs themselves rarely have issues because they are simple blocks of steel. The most common reason to replace a wheel hub is because the bearing that is attached to it has failed. Wheel bearings can fail because of age, dirt and water contamination, or improper installation. Most hubs that are driven by axles require a very specific torque when installing. If that torque is too tight or too loose, the life of the wheel bearing can become shortened. That said, most wheel hub and bearing assemblies are very do-it-yourself friendly. If you can replace brakes yourself, you probably won't have any trouble with a hub either.
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